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Sickle Cell Disease: Splenic Sequestration - OBGYN Associates
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Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Sickle Cell Disease: Splenic Sequestration

Overview

Splenic sequestration is a problem with the spleen that can happen in people who have sickle cell disease.

It happens when a lot of sickled red blood cells get trapped in the spleen. The spleen can enlarge, get damaged, and not work as it should. When the spleen doesn't work well, a person is more likely to have serious, life-threatening infections with certain types of bacteria.

If splenic sequestration happens suddenly, it can be a life-threatening emergency.

Those affected

This condition is more common in infants and young children who have sickle cell disease. It may follow a respiratory infection.

In older children and adults, the spleen often doesn't work because of years of damage from sickled cells.

What are the symptoms?

Splenic sequestration causes sudden and severe anemia, with symptoms of sudden weakness, pale lips, rapid breathing, excessive thirst, belly pain, and rapid heartbeat. Splenic sequestration can happen in people who have sickle cell disease.

Related Information

Credits

Current as of: December 13, 2023

Author: Ignite Healthwise, LLC Staff
Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Current as of: December 13, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.